Login

EnzymeX Logo

Predict enzyme commission (EC) numbers from protein sequences using deep learning

Start Predicting

How It Works

1. Upload Sequence

Paste your protein sequence in FASTA format

2. Obtain EC Number Predictions from Various Models

EC number predictions from HIT-EC, ECPICK, and CLEAN

3. Check the Results

Receive EC number predictions with confidence scores and evidences

EC Number Prediction Models

Three deep learning approaches for EC number prediction

HIT-EC

Trustworthy prediction of enzyme commission numbers using a hierarchical interpretable transformer

Dumontet, L., Han, S.-R., Oh, T.-J., & Kang, M. (2026). Nature Communication

ECPICK

Evidential deep learning for trustworthy prediction of enzyme commission number

Han, S.-R., Park, M., Kosaraju, S., Lee, J., Lee, H., Lee, J. H., Oh, T.-J., & Kang, M. (2024). Briefings in Bioinformatics

CLEAN

Enzyme function prediction using contrastive learning


Yu, T., Cui, H., Li, J. C., Luo, Y., Jiang, G., & Zhao, H. (2023). Science

419
Completed Predictions

Developed by

EnzymeX Logo